Endocrine Abstracts

Introduction: Neurodegeneration is one of the most common condition accompanied Diabetes Mellitus, Parkinson’s and Alzheimer’s diseases. Although its mechanisms intensively studied for many years, some questions of pathogenesis remain unclear. The aim of the study was investigate the effects of thyroid hormones and some neurotransmitters on the cerebral cortex of rats with experimental neurodegeneration. Materials and methods: Series of experim...

Background: In Pathogenesis of Neurodegeneration in Diabetes Mellitus (DM) addition to insulin resistance, glycemic control and blood plasma lipid levels existing other mechanisms were proposed. We investigated plasma insulin level in patients according to severity of diabetic neuropathy.Materials and methods: In 32 people with DM2 glycemia, HbA1c, blood plasma insulin, blood total cholesterol, triglycerides, Low Density Lipoproteins (LDLP) levels were m...